Reprogramming progenitor compositions and methods of use therefore
US10920199B2 · kind B2 · utility
4Cited by
0References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2016 |
| Grant date | Feb 16, 2021 |
| Priority date | — |
| Expiry date | Feb 26, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/1307
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency. In particular embodiments the invention is predicated upon increased expression of an estrogen related receptor and changes in the oxidative and glycolytic pathways.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.