Inventor · Village of La Jolla, CA, US

Michael Downes

50Patents
7h-index
46Co-inventors
72Inventor score

Filing activity: Mar 10, 2000 → Jul 19, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US8999929B2 Fibroblast growth factor 1 protein fragments and methods of use Chemistry; Metallurgy 56 Active
US9072708B2 Methods for treating metabolic disorders using FGF Human Necessities 19 Active
US8906854B2 Methods for treating metabolic disorders using FGF Human Necessities 19 Active
US6673587B1 Histone deacetylase, and uses therefor Chemistry; Metallurgy 13 Expired
US9938234B2 PPAR agonists Chemistry; Metallurgy 12 Active
US10035819B2 PPAR agonists and methods of use thereof Chemistry; Metallurgy 11 Active
US9446097B2 Methods for treating metabolic disorders using FGF Human Necessities 8 Active
US10077268B2 FXR agonists and methods for making and using Chemistry; Metallurgy 7 Active
US10399958B2 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof Chemistry; Metallurgy 6 Active
US9546379B2 Compositions and methods for treating type 1 and type 2 diabetes and related disorders Chemistry; Metallurgy 6 Active
US8212006B2 Structure of the farnesoid X receptor ligand binding domain and methods of use therefor Physics 6 Active
US10479775B1 PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof Chemistry; Metallurgy 6 Active
US9808508B2 Methods for treating metabolic disorders using FGF Human Necessities 5 Active
US9925243B2 Chimeric fibroblast growth factor (FGF) 2/FGF1 peptides and methods of use Chemistry; Metallurgy 5 Active
US9925241B2 Mutated fibroblast growth factor (FGF) 1 and methods of use Chemistry; Metallurgy 5 Active
US8318708B2 Use of vitamin D receptor agonists, ligands, and precursors to treat pancreatic fibrosis Physics 4 Active
US10912800B2 Compositions and methods for treating type 1 and type 2 diabetes and related disorders Chemistry; Metallurgy 4 Active
US7671085B2 Non-steroidal farnesoid X receptor modulators and methods for the use thereof Chemistry; Metallurgy 4 Expired
US10920199B2 Reprogramming progenitor compositions and methods of use therefore Chemistry; Metallurgy 4 Active
US10293027B2 Methods for treating metabolic disorders using FGF Human Necessities 2 Active
US10301268B2 Analogs of fexaramine and methods of making and using Chemistry; Metallurgy 2 Active
US9895381B2 Vitamin D receptor agonists to treat diseases involving CXCL12 activity Human Necessities 2 Active
US9872866B2 Vitamin D receptor/SMAD genomic circuit gates fibrotic response Physics 2 Active
US10159711B2 Methods for treating metabolic disorders using FGF Human Necessities 2 Active
US9192601B2 Methods for enhancing muscle performance and tone Chemistry; Metallurgy 1 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.