7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof

US10927109B2 · kind B2 · utility

Assignees

• BAYER HEALTHCARE LLC · DE
• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Henrik Teller · Schwaan, DE
• Alexandros Vakalopoulos · Hilden, DE
• Melissa BOULTADAKIS ARAPINIS · Düsseldorf, DE
• Alexander Straub · Wuppertal, DE
• Hanna Tinel · Wuppertal, DE
• Markus BRECHMANN · Marburg, DE
• Matthias Beat WITTWER · Riehen, CH
• Maximilian Andreas Kullmann · Leichlingen, DE
• Till FREUDENBERGER · Velbert, DE
• Thomas MONDRITZKI · Essen, DE
• Tobias Marquardt · Wuppertal, DE

Key dates

• Filing date: Sep 6, 2017
• Grant date: Feb 23, 2021
• Expiry date: Sep 6, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application relates to novel 7-substituted 1-arylnaphthyridine-3-carboxamides, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prevention of diseases, and to their use for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders and/or renal disorders.