Methods, models, systems, and apparatus for identifying target sequences for Cas enzymes or CRISPR-Cas systems for target sequences and conveying results thereof

US10930367B2 · kind B2 · utility

Assignees

• The Broad Institute, Inc. · US
• Massachusetts Institute of Technology · US
• President and Fellows of Harvard College · US

Inventors

• Feng Zhang · Cambridge, US
• Yinqing Li · Cambridge, US
• David A. Scott · Cambridge, US
• Joshua Weinstein · Holon, IL
• Patrick Hsu · Cambridge, US

Key dates

• Filing date: Jun 12, 2015
• Grant date: Feb 23, 2021
• Expiry date: Dec 9, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/11
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed are thermodynamic and multiplication methods concerning CRISPR-Cas systems, and apparatus therefor.