Cyclic peptides with enhanced nerve-binding selectively, nanoparticles bound with said cyclic peptides, and use of same for real-time in vivo nerve tissue imaging

US10940216B2 · kind B2 · utility

Assignees

• Cornell University · IT
• Memorial Sloan Kettering Cancer Center · US

Inventors

• Michelle S. Bradbury · Andover, US
• Barney Yoo · New York, US
• Ulrich Wiesner · Ithaca, US
• Peiming Chen · New York, US
• Kai Ma · Ithaca, US
• Snehal G. Patel · New York, US
• Daniella Karassawa Zanoni · New York, US

Key dates

• Filing date: May 17, 2019
• Grant date: Mar 9, 2021
• Expiry date: May 17, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K49/0093
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are cyclic peptides, nanoparticles bound with cyclic peptides, and methods for using said cyclic peptides and/or said nanoparticles bound with cyclic peptides for intraoperative nerve tissue imaging.