Patent assignee · US · COMPANY

Memorial Sloan Kettering Cancer Center

552Patents
492Active
552Granted
62Portfolio score

Filing activity: Sep 1, 1982 → Feb 23, 2024 · 24 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US6350861B1 Antibodies with increased binding affinity Chemistry; Metallurgy 316 Expired
US8389282B2 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Emerging Cross-Sectional Technologies 208 Active
US6520183B2 Double endobronchial catheter for one lung isolation anesthesia and surgery Emerging Cross-Sectional Technologies 171 Expired
US6933368B2 Increasing antibody affinity by altering glycosylation of immunoglobulin variable region Chemistry; Metallurgy 140 Expired
US6316208A Methods for determining isolated p27 protein levels and uses thereof Physics 111 Expired
US7442507B2 Methods for detecting circulating mutant BRAF DNA Chemistry; Metallurgy 103 Active
US6825203B2 Topical anesthetic/opioid formulations and uses thereof Human Necessities 84 Expired
US7314721B2 Small cell lung cancer associated antigens and uses therefor Human Necessities 81 Expired
US6310185A Recombinant human anti-Lewis Y antibodies Chemistry; Metallurgy 58 Expired
US6813568B2 System and process for microfluidics-based automated chemistry Physics 54 Expired
US4559309A Flow cytometry-fluorescence measurements for characterizing sperm Emerging Cross-Sectional Technologies 54 Expired
US10221461B2 Immunocompetence assessment by adaptive immune receptor diversity and clonality characterization Physics 45 Active
US9606245B1 Autonomous gamma, X-ray, and particle detector Physics 42 Active
US5342757A Monoclonal antibodies which specifically binds to endosialin, a 165 Kd glycoprotein found on tumor vascular endothelium, and uses thereof Emerging Cross-Sectional Technologies 42 Expired
US9220728B2 Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes Emerging Cross-Sectional Technologies 36 Active
US9840533B2 Compositions and methods for altering second messenger signaling Physics 35 Active
US5646253A Recombinant human anti-LK26 antibodies Physics 31 Expired
US9540448B2 T cell receptor-like antibodies specific for a WTI peptide presented by HLA-A2 Chemistry; Metallurgy 27 Active
US9074000B2 T cell receptor-like antibodies specific for a WT1 peptide presented by HLA-A2 Chemistry; Metallurgy 26 Active
US8709417B2 Combination immunotherapy for the treatment of cancer Chemistry; Metallurgy 26 Active
US4743540A Method for diagnosis of subclassifications of common varied immunodeficiency disease group Emerging Cross-Sectional Technologies 24 Expired
US5804381A Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof Human Necessities 23 Expired
US10963673B2 Identifying regions of interest from whole slide images Physics 19 Active
US9567318B2 Substituted pyrimidine compounds and uses thereof Human Necessities 19 Active
US5874060A Recombinant human anti-Lewis Y antibodies Chemistry; Metallurgy 19 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.