Formation of stable cartilage

US10940241B2 · kind B2 · utility

Assignees

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US
• HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. · IL

Inventors

• Pamela Gehron Robey · Bethesda, US
• Sergei Kuznetsov · Rockville, US
• Raphael Gorodetsky · Jerusalem, IL
• Astar Hailu-Lazmi · Jerusalem, IL
• Mitchell Shirvan · Kfar Sava, IL
• Joseph Featherall · Cleveland, US

Key dates

• Filing date: May 31, 2018
• Grant date: Mar 9, 2021
• Expiry date: May 31, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods are provided for promoting cartilage growth and/or repair. The methods include, administering locally to a site in a subject in need thereof, bone marrow stromal cells attached to fibrin microbeads comprising crosslinked hyaluronic acid and thereby producing stable cartilage locally at the site in the subject.