Patent · US Active

Polymerase variants

US10961520B2 · kind B2 · utility

0Cited by

2References

5Claims

0Family size

Assignees

Roche Molecular Systems, Inc. · US
Roche Sequencing Solutions, Inc. · US

Inventors

Aruna Ayer · Santa Clara, US
Cleoma Arnold · San Jose, US
Arkadiusz Bibillo · Cupertino, US
Mara Boenitz-Dulat · Tutzing, DE
Barbara Eckert · Corona, US
Ilya Lederman · San Francisco, US
Colin Alexander McGaw · Santa Clara, US
Charles Wayan Schwab · San Ramon, US
Tyler O'Brien Shultz · Santa Clara, US
Shawn Suko · El Sobrante, US
Eileen Thai · San Jose, US
Bigna Woersdoerfer · Munich, DE
David Daniel Wunderlich · Penzberg, DE

Key dates

Filing date	Feb 26, 2020
Grant date	Mar 30, 2021
Priority date	—
Expiry date	Feb 26, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y207/07007
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365Q, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652, K655, W656, D657, V658, H660, F662, L690 and combinations thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.