Patent · US Active

Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof

US10988534B2 · kind B2 · utility

1Cited by

23References

16Claims

0Family size

Assignees

Inventors

Sarah M. Cheal · New York, US
Hong Xu · San Diego, US
Steven M. Larson · New York, US
Nai-Kong V. Cheung · New York, US
Karl Dane Wittrup · Urbana, US
Alice Tzeng · Beachwood, US

Key dates

Filing date	Feb 9, 2016
Grant date	Apr 27, 2021
Priority date	—
Expiry date	Jul 15, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/33
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.