Patent · US Active

Distance-based tumor classification

US11017533B2 · kind B2 · utility

1Cited by

2References

17Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Fabien Gaire · Starnberg, DE
Oliver Grimm · Schwerin, DE
Hadassah Sumum Sade · Penzberg, DE
Suzana Vega Harring · Starnberg, DE

Key dates

Filing date	Nov 2, 2017
Grant date	May 25, 2021
Priority date	—
Expiry date	Dec 7, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG06T2207/30096
WIPO fieldComputer technology
WIPO sectorElectrical engineering

Abstract

The system is configured to receive at least one digital image of a tissue sample of a patient; analyze the at least one received image for identifying tumor cells in a region of the at least one received image; analyze the at least one received image for identifying FAP+ areas in the region, each FAP+ area being a pixel blob representing one or more cells express the fibroblast activation protein—“FAP”; analyze the at least one received image for identifying distances between the identified tumor cells and their respective nearest FAP+ area; computing a proximity measure as a function of the identified distances; process the proximity measure by a classifier for generating a classification result, the classification result indicating if the tumor of the patient can be treated by a drug or drug-component that binds to FAP; and output the classification result.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.