Substituted 6-membered aryl or heteroaryl allosteric modulators of nicotinic acetylcholine receptors
US11026958B2 · kind B2 · utility
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Key dates
| Filing date | Oct 30, 2017 |
| Grant date | Jun 8, 2021 |
| Priority date | — |
| Expiry date | Apr 30, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/0812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to compounds of formula (I) that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.