Macrocyclic broad spectrum antibiotics
US11072635B2 · kind B2 · utility
0Cited by
9References
20Claims
0Family size
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Key dates
| Filing date | Nov 21, 2016 |
| Grant date | Jul 27, 2021 |
| Priority date | — |
| Expiry date | Nov 21, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.