Patent · US Active

Combination therapy for the treatment of cancer

US11078279B2 · kind B2 · utility

2Cited by
65References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 9, 2016
Grant dateAug 3, 2021
Priority date
Expiry dateJun 17, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to a pharmaceutical composition that comprises a first molecule that specifically binds HER2/neu and a second molecule that specifically binds a cell-surface receptor (or its ligand) that is involved in regulating an immune checkpoint (or the ligand thereof). The invention particularly relates to the embodiment wherein the second molecule binds to PD-1. The invention also relates to the use of such pharmaceutical compositions to treat cancer and other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.