Patent · US Active

Photocleavable nucleotide reagents with high stability

US11078534B2 · kind B2 · utility

0Cited by

1References

7Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Alexander Nierth · Dublin, US
Hannes Kuchelmeister · Munich, DE
Concordio Anacleto · Dublin, US
Amar Gupta · Danville, US
Dieter Heindl · Munich, DE
Igor Kozlov · Danville, US
Christian Wellner · Penzberg, DE
Stephen G. Will · Oakland, US

Key dates

Filing date	Nov 26, 2018
Grant date	Aug 3, 2021
Priority date	—
Expiry date	Oct 31, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/686
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention provides for stable nucleotide reagents used for nucleic acid amplification by PCR and RT-PCR (Reverse Transcriptase-PCR) that comprises modified nucleoside triphosphates. The present invention also provides for methods for using the modified nucleoside triphosphates for detecting the presence or absence of a target nucleic acid sequence in a sample in an amplification reaction.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.