Optimized PNE-based chimeric receptor T cell switches and uses thereof
US11091546B2 · kind B2 · utility
3Cited by
27References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2016 |
| Grant date | Aug 17, 2021 |
| Priority date | — |
| Expiry date | Jul 18, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are chimeric antigen receptor effector cells (CAR-ECs) and CAR-EC switches. The switchable CAR-ECs are generally T cells. The one or more chimeric antigen receptors may recognize a peptidic antigen on the CAR-EC switch. The CAR-ECs and switches may be used for the treatment of a condition in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.