Helical polycarbodiimide polymers and associated imaging, diagnostic, and therapeutic methods
US11097019B2 · kind B2 · utility
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Key dates
| Filing date | Dec 31, 2018 |
| Grant date | Aug 24, 2021 |
| Priority date | — |
| Expiry date | Jan 19, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/587
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are suspensions of helical polycarbodiimide polymers that ‘cloak’ nanotubes, thereby effecting control over nanotube emission, providing a new mechanism of environmental responsivity, and enabling precise control over sub-cellular localization. The helical polycarbodiimide polymers described herein are water soluble, easily modifiable, and have unique architectures that facilitate their application in radiopharmaceutical delivery and imaging methods, in therapeutics and therapeutic delivery methods, and their use as sensors—both in conjunction with carbon nanotubes, and without nanotubes.
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