Pyridazinones and their use in the treatment of cancer

US11110089B2 · kind B2 · utility

Assignees

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US
• Elias Set Jenö Arnér · SE

Inventors

• Elias Set Jenö Arnér · Stockholm, SE
• William Stafford · Älta, SE
• Nathan Patrick Coussens · Vienna, US
• Diane K. Luci · Germantown, US
• David J. Maloney · Point of Rocks, US
• Anton Simeonov · Rockville, US
• Ajit Jadhav · Chantilly, US
• Thomas S. Dexheimer · Lansing, US

Key dates

• Filing date: Aug 5, 2016
• Grant date: Sep 7, 2021
• Expiry date: Feb 22, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is provided compounds of formula (I) or pharmaceutically-acceptable salts thereof, wherein W, X, Y, Z, R1, R2 and R3 have meanings provided in the description, which compounds are useful in the treatment of cancers.