Patent · US Active

Multispecific antigen-binding proteins

US11116840B2 · kind B2 · utility

2Cited by

106References

16Claims

0Family size

Assignee

Genentech, Inc. · US

Inventors

Paul Carter · San Francisco, US
Christoph Spiess · South San Francisco, US
Yiyuan Yin · Fremont, US
Jianhui Zhou · Beijing, CN
Wendy SANDOVAL · San Francisco, US
Jacob Corn · Berkeley, US
Michael DILLON · San Francisco, US

Key dates

Filing date	Oct 20, 2017
Grant date	Sep 14, 2021
Priority date	—
Expiry date	Jul 30, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG16B20/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.