Patatin-like phospholipase domain containing 3 (PNPLA3) iRNA compositions and methods of use thereof
US11149276B2 · kind B2 · utility
1Cited by
4References
30Claims
0Family size
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Key dates
| Filing date | Feb 23, 2021 |
| Grant date | Oct 19, 2021 |
| Priority date | — |
| Expiry date | Apr 17, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2750/14143
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi agents, e.g., double stranded RNA (dsRNA) agents, targeting the Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene. The invention also relates to methods of using such RNAi agents to inhibit expression of a PNPLA3 gene and to methods of preventing and treating an PNPLA3-associated disorder, e.g., Nonalcoholic Fatty Liver Disease (NAFLD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.