CRISPR-Cas systems, crystal structure and uses thereof
US11155795B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jun 2, 2016 |
| Grant date | Oct 26, 2021 |
| Priority date | — |
| Expiry date | Oct 11, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2299/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.