Antibodies that target HIV GP120 and methods of use

US11168130B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Mini Balakrishnan · San Mateo, US
• Brian Carr · Raleigh, US
• Craig S. Pace · Pacifica, US
• Doug Rehder · Bonsall, US
• Matthew R. Schenauer · Dana Point, US
• Loredana Serafini · Orinda, US
• Heather Stephenson · San Jose, US
• Nathan D. Thomsen · Castro Valley, US
• Helen Yu · Mountain View, US
• Xue Zhang · Beijing, CN

Key dates

• Filing date: Jul 2, 2019
• Grant date: Nov 9, 2021
• Expiry date: Jul 2, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.