Patent · US Active

Antibodies binding to HLA-A2/WT1

US11192957B2 · kind B2 · utility

0Cited by

36References

38Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Joerg Benz · Rheinfelden (Baden), DE
Christian Klein · Iffeldorf, DE
Stefan Klostermann · Schwanau, DE
Ekkehard Moessner · Kreuzlingen, CH
Johannes SAM · Schlieren, CH
Pablo Umana · Wollerau, CH
Lydia Jasmin Hanisch · Schlieren, CH
Alexander BUJOTZEK · Penzberg, DE
Wei Xu · Saginaw, US

Key dates

Filing date	Dec 20, 2018
Grant date	Dec 7, 2021
Priority date	—
Expiry date	Apr 26, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention generally relates to antibodies that bind to HLA-A2/WT1, including bispecific antigen binding molecules e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.