Macrocyclic broad spectrum antibiotics
US11208387B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | May 27, 2020 |
| Grant date | Dec 28, 2021 |
| Priority date | — |
| Expiry date | May 27, 2040 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidases SpsB and/or LepB, an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.