Substituted phenyl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors

US11208407B2 · kind B2 · utility

Assignee

• Merck Sharp & Dohme LLC · US

Inventors

• Hua Zhou · Acton, US
• Abdelghani Achab · Melrose, US
• Xavier Fradera · Brookline, US
• Yongxin Han · Kirkland, CA
• Derun Li · Dedham, US
• Meredeth A. McGowan · Boston, US
• Nunzio Sciammetta · Sudbury, US
• David L. Sloman · Brookline, US
• Wensheng Yu · Edison, US

Key dates

• Filing date: Jul 30, 2018
• Grant date: Dec 28, 2021
• Expiry date: Jul 30, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (I) Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.