Polysaccharide-protein conjugates utilizing diphtheria toxin fragment B as a carrier
US11219680B2 · kind B2 · utility
1Cited by
4References
10Claims
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Key dates
| Filing date | Feb 20, 2018 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Feb 20, 2038 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides immunogenic compositions having one or more polysaccharide-protein conjugates in which polysaccharides obtained from bacterial capsules are conjugated to diphtheria toxin fragment B (DTFB) or a variant thereof. The immunogenic compositions may be multivalent pneumococcal polysaccharide conjugate compositions in which polysaccharides from one or more Steptococcus pneumoniae serotypes are conjugated to diphtheria toxin fragment B (DTFB) and, optionally, additional polysaccharides from one or more different Steptococcus pneumoniae serotypes are conjugated to one or more other carrier proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.