Patent · US Active

[18F]-labelled lactate derivative as PET radiotracer

US11260036B2 · kind B2 · utility

0Cited by

2References

9Claims

0Family size

Assignee

GRANDIS · US

Inventors

Pierre Sonveaux · Ottignies-Louvain-la-Neuve, BE
Daniel Labar · Grand-Leez, BE
Vincent Van Hée · Braine-l'Alleud, BE
Gwenaël Dehon · Seneffe, BE
Raphaël FRÉDÉRICK · Godinne, BE

Key dates

Filing date	Sep 9, 2020
Grant date	Mar 1, 2022
Priority date	—
Expiry date	Sep 9, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C59/115
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A positron emission tomography (PET) radiotracer for imaging lactate uptake, wherein the tracer is [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Also, a process for the radiosynthesis of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof. Further, the use of [18F]-3-fluoro-2-hydroxypropionic acid, or a pharmaceutical acceptable salt and/or solvate thereof, for imaging lactate uptake in living cells, especially in humans.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.