Patent · US Active

Escherichia coli compositions and methods thereof

US11260119B2 · kind B2 · utility

3Cited by
10References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 7, 2019
Grant dateMar 1, 2022
Priority date
Expiry dateAug 7, 2039

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.