Methods for regulating nitrogen metabolism during the production of ethanol from corn by metabolically engineered yeast strains
US11274319B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Sep 13, 2019 |
| Grant date | Mar 15, 2022 |
| Priority date | — |
| Expiry date | Sep 13, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for a mechanism to reduce glycerol production and increase nitrogen utilization and ethanol production of recombinant microorganisms. One aspect of this invention relates to strains of S. cerevisiae with reduced glycerol productivity that get a kinetic benefit from higher nitrogen concentration without sacrificing ethanol yield. A second aspect of the invention relates to metabolic modifications resulting in altered transport and/or intracellular metabolism of nitrogen sources present in corn mash.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.