Patent · US Active

Methods and systems for sequence calling

US11276480B2 · kind B2 · utility

8Cited by
1References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 19, 2021
Grant dateMar 15, 2022
Priority date
Expiry dateAug 19, 2041

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16B45/00
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

The present disclosure provides methods and systems for accurate and efficient context-aware base calling of sequences. In an aspect, disclosed herein is a method for sequencing a nucleic acid molecule, comprising: (a) sequencing the nucleic acid molecule to generate a plurality of sequence signals; and (b) determining base calls of the nucleic acid molecule based at least in part on (i) the plurality of sequence signals and (ii) quantified context dependency for at least a portion of the plurality of sequence signals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.