Compositions and methods for the inhibition of pruritus

US11324725B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Secretary, Department of Health and Human Services · US

Inventors

• Mark Hoon · Kensington, US
• Hans Juergen Solinski · Itzehoe, DE
• James Inglese
• Patricia Dranchak · Gaithersburg, US

Key dates

• Filing date: Nov 2, 2018
• Grant date: May 10, 2022
• Expiry date: Dec 15, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical compositions comprising a molecular inhibitor of Npr1 are disclosed. Also disclosed are methods of treating, reducing, or preventing acute and/or chronic pruritus in a mammal comprising administering a pharmaceutical composition comprising a molecular inhibitor of Npr1.