Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors
US11332463B2 · kind B2 · utility
1Cited by
6References
54Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 29, 2019 |
| Grant date | May 17, 2022 |
| Priority date | — |
| Expiry date | May 24, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure relates to compounds of formula I that are useful as modulators of 7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.