Short syntheses of (−)-picrotoxinin and related compounds
US11351147B2 · kind B2 · utility
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Key dates
| Filing date | Aug 6, 2020 |
| Grant date | Jun 7, 2022 |
| Priority date | — |
| Expiry date | Aug 6, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to concise processes for making (−)-picrotoxinin (1, PXN) and 5-methyl-picrotoxinin (20, 5MePXN), and to 5MePXN, its pharmaceutical compositions, and its method of use for inhibiting GABAA receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.