Composition and methods for inhibiting mammalian sterile 20-like kinase 1

US11427560B2 · kind B2 · utility

Assignees

• THE SCRIPPS RESEARCH INSTITUTE · US
• UNIVERSITÄT BREMEN · DE

Inventors

• Hank Michael James Petrassi · San Diego, US
• Murali Mohan Reddy Peram Surakattula · San Diego, US
• Kathrin MAEDLER · Bremen, DE
• Amin ARDESTANI · Bremen, DE
• Jason Thomas Roland · San Diego, US
• Tyler D. Baguley · San Diego, US
• Matthew S. TREMBLAY · San Diego, US
• Weijun Shen · San Diego, US
• Peter G. Schultz · Village of La Jolla, US
• Arnab K. Chatterjee · Encinitas, US

Key dates

• Filing date: Aug 20, 2020
• Grant date: Aug 30, 2022
• Expiry date: Aug 20, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y207/11001
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compounds, compositions, and methods of their use for the treatment of diabetes.