Complement factor based affinity chromatography

US11440942B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Alexander KNAUPP · Penzberg, DE
• Laurent Lariviere · Ostendorf, DE
• Petra Rueger · Penzberg, DE
• Tilman Schlothauer
• Stefan Seeber · Penzberg, DE

Key dates

• Filing date: Mar 15, 2019
• Grant date: Sep 13, 2022
• Expiry date: Sep 18, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/4716
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

Herein is reported a fusion polypeptide according to formula I (TAG-X1-C1qA-X2-C1qB-X3-C1qC-X4), comprising a fragment of SEQ ID NO: 01 (C1qA), a fragment of SEQ ID NO: 03 (C1qB), a fragment of SEQ ID NO: 05 (C1qC) and optionally a tag (TAG).