Optical device for non-invasive continuous monitoring of blood glucose level and HbA1c concentration
US11452469B1 · kind B1 · utility
Inventor
Key dates
| Filing date | Sep 24, 2021 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | Sep 24, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2562/0238
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source emitting in 2 um to 10 um range for exciting the target species and a probe beam with orthogonal polarizations and split frequencies in the KHz. to MHz range. The probe beam measures the effects of specie concentration change and of its excitation. The evanescent fields of the orthogonally polarized beams in the probe beam undergo differential phase shifts when target species concentration changes in epidermis or when its refractive index changes due to photo-thermal excitation by the MIR beam. The phase shift is directly proportional to concentration change and refractive index change and are measured using a heterodyne interferometer operating at the same frequency as the split frequency. The measured phase shift can be related to specie concentration change in target volume.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.