Cyclic di-nucleotide compounds as sting agonists
US11453697B1 · kind B1 · utility
1Cited by
11References
10Claims
0Family size
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Key dates
| Filing date | Jun 18, 2020 |
| Grant date | Sep 27, 2022 |
| Priority date | — |
| Expiry date | Nov 28, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7084
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of polycyclic compounds of general formula (I), of general formula (I′), or of general formula (I″), wherein Base1, Base2, Y, Ya, Xa, Xa1, Xb, Xb1, Xc, Xc1, Xd, Xd1, R1, R1a, R2, R2a, R3, R4, R4a, R5, R6, R6a, R7, R7a, R8, and R8a are defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.