Method for detecting multispecific antibody light chain mispairing

US11486882B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Michael Molhoj · Munich, DE
• Maximiliane Koenig · Pullach, DE
• Vincent Larraillet · Penzberg, DE
• Katja Montan · Munich, DE
• Bianca Gruenwalder · Bad Heilbrunn, DE

Key dates

• Filing date: May 20, 2019
• Grant date: Nov 1, 2022
• Expiry date: Mar 30, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/6857
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Use of a limited digestion with a proteolytic enzyme of a multispecific antibody for the analysis of the multispecific antibody's light chain pairing.