T cell receptor-like antibodies specific for Foxp3-derived peptides
US11505599B2 · kind B2 · utility
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14References
11Claims
0Family size
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Key dates
| Filing date | Jan 13, 2017 |
| Grant date | Nov 22, 2022 |
| Priority date | — |
| Expiry date | Feb 7, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The presently disclosed subject matter provides antigen-binding proteins (e.g., chimeric antigen receptors) and antibodies or antigen-binding portions thereof that bind to a Foxp3 peptide/MHC molecule complex. Such antibodies, fusion proteins and conjugates thereof are useful for inhibiting regulatory T cells and treating cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.