Patent · US Active

Multiplex PCR detection of ALK, RET, and ROS fusions

US11505830B2 · kind B2 · utility

0Cited by

0References

25Claims

0Family size

Assignee

Roche Molecular Systems, Inc. · US

Inventors

Ann Begovich · Corona, US
Cindy Cheung · Fremont, US
Javelin Chi · Pleasanton, US
Grantland Hillman · Oakland, US
Dwight Kuo · Castro Valley, US
Michael Lee · Lake Oswego, US
Chitra Manohar · San Ramon, US
Xiaoju Max Ma · San Carlos, US
Ellen Ordinario · Oakland, US
Jaya Rajamani · Pleasanton, US
Huan Truong · Milpitas, US

Key dates

Filing date	May 30, 2018
Grant date	Nov 22, 2022
Priority date	—
Expiry date	May 30, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/166
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided herein are methods and compositions for multiplex detection of a large number of actionable gene fusions with very high sensitivity and specificity. The present methods and compositions can detect ALK, RET, and ROS1 gene fusions, optionally in combination with other mutations and fusions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.