Compositions and methods for detecting and quantifying host cell protein in cell lines and recombinant polypeptide products
US11519912B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Mar 7, 2018 |
| Grant date | Dec 6, 2022 |
| Priority date | — |
| Expiry date | May 20, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Monoclonal and polyclonal antibodies that bind hamster phospholipase B-like 2 are provided. Also provided are methods for detecting and quantifying hamster phospholipase B-like 2, for example, in recombinant polypeptide preparations, as well as kits for carrying out such methods. Methods of screening or selecting host cell lines or recombinant polypeptide-expressing cell lines that express low levels of hamster phospholipase B-like 2 are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.