Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems
US11572595B2 · kind B2 · utility
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7References
2Claims
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Key dates
| Filing date | Dec 20, 2019 |
| Grant date | Feb 7, 2023 |
| Priority date | — |
| Expiry date | Oct 13, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/31
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to compositions comprising and methods of producing genetically engineered bacteriophages, bacteriophage-like particles and non-replicating transduction particles (NRTPs) that contain non-native tail fibers that display altered host specificity and/or reactivity. The present invention also relates to methods of using these bacteriophages and NRTPs for the development of novel diagnostics, therapeutics and/or research reagents for bacteria-related diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.