Compositions and methods for reprogramming somatic cells into induced vasculogenic cells
US11578107B2 · kind B2 · utility
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Key dates
| Filing date | Dec 20, 2017 |
| Grant date | Feb 14, 2023 |
| Priority date | — |
| Expiry date | Nov 2, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/1307
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and methods that involve using compositions containing one or more of ETV2, FOXC2, FLI1 and a miR-200b inhibitor for directly reprogramming somatic cells into induced vasculogenic cells both in vitro and in vivo. These compositions and methods are useful for a variety of purposes, including the development of pro-angiogenic therapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.