Methods of treating a retroviral infection

US11583581B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Matthias Schroff · Berlin, DE
• Manuel Schmidt · Berlin, DE
• Kerstin Kapp · Berlin, DE
• Alfredo Zurlo · Berlin, DE
• Ole Schmeltz Sogaard · Berlin, DE
• Martin Tolstrup · Berlin, DE
• Rasmus Offersen · Berlin, DE

Key dates

• Filing date: Sep 21, 2016
• Grant date: Feb 21, 2023
• Expiry date: Apr 26, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2320/31
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a non-coding sequence of deoxyribonucleic acids comprising at least one sequence motif N1N2CGN3N4, wherein N is a nucleotide comprising A, C, T, or G, and C is deoxycytidine, G is deoxyguanosine, A is deoxyadenosine and T is deoxy-thymidine for the treatment of viral infections. In particular, the non-coding sequence of deoxyribonucleic acids is used in combination with antiretroviral therapy and/or histone de-acetylase inhibitors.