Patent · US Active

Devices and methods for molecule detection based on thermal stabilities of magnetic nanoparticles

US11609208B2 · kind B2 · utility

0Cited by
56References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 26, 2019
Grant dateMar 21, 2023
Priority date—
Expiry dateAug 28, 2040

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01R33/007
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed herein are detection devices, systems, and methods that use magnetic nanoparticles (MNPs) to allow molecules to be identified. Embodiments of this disclosure include magnetic sensors (e.g., magnetoresistive sensors) that can be used to detect temperature-dependent magnetic fields (or changes in magnetic fields) emitted by MNPs, and, specifically to distinguish between the presence and absence of magnetic fields emitted, or not emitted, by MNPs at different temperatures selected to take advantage of knowledge of how the MNPs' magnetic properties change with temperature. Embodiments disclosed herein may be used for nucleic acid sequencing, such as deoxyribonucleic acid (DNA) sequencing.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.