Angiopoietin-like 3 (ANGPTL3) iRNA compositions and methods of use thereof
US11613751B2 · kind B2 · utility
3Cited by
10References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2022 |
| Grant date | Mar 28, 2023 |
| Priority date | — |
| Expiry date | Mar 8, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/351
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to RNAi agents, e.g., double stranded RNA (dsRNA) agents, targeting the Angiopoietin-like 3 (ANGPTL3) gene. The invention also relates to methods of using such RNAi agents to inhibit expression of an ANGPTL3 gene and to methods of preventing and treating an ANGPTL3-associated disorder, e.g., a disorder of lipid metabolism, such as hyperlipidemia or hypertriglyceridemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.