Type V CRISPR-Cas systems and use thereof

US11639523B2 · kind B2 · utility

Assignees

• The Broad Institute, Inc. · US
• Massachusetts Institute of Technology · US

Inventors

• Feng Zhang · Cambridge, US
• Jonathan Gootenberg · Cambridge, US
• Omar Abudayyeh · Cambridge, US
• Julia Joung · Cambridge, US
• Alim Ladha · Cambridge, US
• Han Altae-Tran · Cambridge, US
• Guilhem Faure · Cambridge, US

Key dates

• Filing date: Jun 5, 2020
• Grant date: May 2, 2023
• Expiry date: Jun 5, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/165
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Engineered or non-naturally occurring systems and compositions comprising a novel Cas12b and a guide molecule. Also provided include methods of use the systems and compositions, including in treating and diagnosing diseases.