Patent · US Active

Anti-coagulation factor XI antibodies

US11661460B2 · kind B2 · utility

1Cited by

36References

67Claims

0Family size

Assignees

Merck Sharp & Dohme LLC · US
Adimab, LLC · US

Inventors

Zhu Chen · Pequest, US
Kenneth Ellsworth · Cranbury, US
James Milligan · New Egypt, US
Elizabeth Oldham · Santa Clara, US
Dietmar Seiffert · Boothwyn, US
Vaishnavi Ganti · San Jose, US
Mohammad Tabrizifard · Moraga, US
Bianka Prinz · Lebanon, US

Key dates

Filing date	May 1, 2020
Grant date	May 30, 2023
Priority date	—
Expiry date	Dec 25, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.