Protective surface coatings for flow cells
US11667969B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 2, 2018 |
| Grant date | Jun 6, 2023 |
| Priority date | — |
| Expiry date | Aug 9, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/165
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An example of a method includes providing a substrate with an exposed surface comprising a first chemical group, wherein the providing optionally comprises modifying the exposed surface of the substrate to incorporate the first chemical group; reacting the first chemical group with a first reactive group of a functionalized polymer molecule to form a functionalized polymer coating layer covalently bound to the exposed surface of the substrate; grafting a primer to the functionalized polymer coating layer by reacting the primer with a second reactive group of the functionalized polymer coating layer; and forming a water-soluble protective coating on the primer and the functionalized polymer coating layer. Examples of flow cells incorporating examples of the water-soluble protective coating are also disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.