Antibody that binds to VEGF-A and ANG2 and methods of use

US11732036B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Roland Beckmann · Wien, AT
• Sebastian Fenn · Clapham, GB
• Guido Hartmann · Soest, DE
• Sabine Imhof-Jung · Planegg, DE
• Kristian Hobolt-Jensen · Penzberg, DE
• Joerg Moelleken · Penzberg, DE
• Michael Molhoj · Munich, DE
• Christian Schantz · Penzberg, DE
• Janina Speck · Penzberg, DE
• Christoph Ullmer · Fischingen, DE
• Barbara Weiser · East Greenbush, US

Key dates

• Filing date: Sep 3, 2021
• Grant date: Aug 22, 2023
• Expiry date: Sep 3, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to anti-VEGF-A/anti-ANG2 antibodies, e.g. in the form of a bispecific Fab fragment, and methods of using the same.