Anti-CD8 antibodies and uses thereof
US11739150B2 · kind B2 · utility
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32References
25Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 11, 2020 |
| Grant date | Aug 29, 2023 |
| Priority date | — |
| Expiry date | Jan 5, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.